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Nicolas Plachta

Title:	Dr
First Name:	Nicolas
Surname:	Plachta
Position:	Group Leader, EMBL Australia Partner Laboratory
Group:	Plachta
Phone No:	+61 3 9902 9612
Email Address:	nicolas.plachta@monash.edu

Research Interests:
Biography:	Dr Plachta is an expert in biological imaging and embryonic development. His research provides insights into how cells and molecules interact during the early stages of life and may provide knowledge key to understanding, preventing and treating a range of diseases. Dr Plachta has recently been able to study key biological processes guiding embryonic development, such as gene expression dynamics, in intact mammalian embryos. Before joining ARMI as the second EMBL Australia Partner Laboratory Network Group Leader, Nicolas worked at the Biological Imaging Centre of the California Institute of Technology and at the Biozentrum of the University of Basel.
Selected Publications:	Plachta N, Bollenbach T, Pease S, Fraser SE, Pantazis P. Oct4 kinetics predict cell lineage patterning in the early mammalian embryo. Nat Cell Biol. 2011 Feb;13(2):117-23. PMID: 21258368 Nikoletopoulou V, Plachta N, Allen ND, Pinto L, Götz M, Barde YA. Neurotrophin receptor-mediated death of misspecified neurons generated from embryonic stem cells lacking Pax6. Cell Stem Cell. 2007 Nov;1(5):529-40. PMID: 18371392 Plachta N, Annaheim C, Bissière S, Lin S, Rüegg M, Hoving S, Müller D, Poirier F, Bibel M, Barde YA. Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells. Nat Neurosci. 2007 Jun;10(6):712-9. PMID: 17486104 Plachta N, Bibel M, Tucker KL, Barde YA. Developmental potential of defined neural progenitors derived from mouse embryonic stem cells. Development. 2004 Nov;131(21):5449-56. PMID: 15469972
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