The ARMI Gene Recombineering Facility was developed by Jeanette Rientjes,
former Head of Gene Expression Core at the EMBL (Monterotondo). It is
unique in Australia, utilising cutting edge genetic manipulation
technology.
The facility provides specialised modification of
genomic material from multiple organisms. This includes
generation of new models of disease for Australian and international
scientists.
The Gene Recombineering Facility provides DNA targeting and transgenic constructs.
Examples of the constructs that we make:
- Shaving BAC clones
- Sub cloning pieces from BAC clones into a high copy plasmid
- Mutant BAC constructs (Cre/FLP constructs, pointmutations in BAC clones, knockin of fluorescent genes)
- Knock out targeting constructs
- Knock in targeting constructs
- Conditional knock out constructs
- Pointmutations (targeting constructs)
- Exon exchange (targeting constructs)
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Gene Recombineering Contact
Jeanette Rientjes
Telephone: +61 3 9902 9730
Mobile: +61 439 317 780
jeanette.rientjes@armi.monash.edu.au
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