Publications


Selected Publications

Heng, JI,  Chariot, A  and  Nguyen,  L.   Molecular layers underlying cytoskeletal remodelling during cortical development.  Trends in Neurosciences. 2010 Jan;33(1):38-47

Merot, Y, Reteaux, S and Heng, JI. Molecular mechanisms of projection neuron migration and maturation in the developing cerebral cortex. Seminars in Cell and Developmental Biology. 2009 Aug;20(6):726-34.

Heng, JI, Nguyen, L.,Castro, D., Zimmer, C., Armant, O., Skowronska-Krawczyk, D., Bedogni, F., Matter, J-M., Hevner, R., Guillemot, F. Neurogenin2 controls cortical neuron migration through regulation of Rnd2. Nature. 2008 Sep 4;455(7209):114-8.

Zhao, X, Heng, JI, Guardavaccaro, D., Pagano, M., Guillemot, F., Iavarone, A., Lasorella, A. The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nature Cell Biology. 2008 Jun;10(6):643-53.5

Heng, JI, Moonen, G., Nguyen, L. Neurotransmitters regulate cell migration in the telencephalon. European Journal of Neuroscience. 2007 Aug;26(3):537-46. (Invited review)

Nguyen L, Besson A, Heng JI, Schuurmans C, Teboul L, Parras C, Philpott A, Roberts JM, Guillemot F. p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex. Genes & Development. 2006 Jun 1;20(11):1511-24.

Ge W, He F, Kim KJ, Blanchi B, Coskun V, Nguyen L, Wu X, Zhao J, Heng JI, Martinowich K, Tao J, Wu H, Castro D, Sobeih MM, Corfas G, Gleeson JG, Greenberg ME, Guillemot F, Sun YE. Coupling of cell migration with neurogenesis by proneural bHLH factors. Proceedings of the National Academy of Sciences USA. 2006 Jan 31;103(5):1319-24.

Hand R, Bortone D, Mattar P, Nguyen L, Heng JI, Guerrier S, Boutt E, Peters E, Barnes AP, Parras C, Schuurmans C, Guillemot F, Polleux F.  Phosphorylation of Neurogenin2 specifies the migration properties and the dendritic morphology of pyramidal neurons in the neocortex. Neuron. 2005 Oct 6;48(1):45-62.
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