Staff Events

Heme and iron metabolism in developing erythroid cells

Barry H. Paw, M.D., Ph.D. Associate Professor, Medicine
Harvard Medical School


Abstract

The focus of Barry Paw’s laboratory research is studying genes important for red cell development, in particular, genes crucial for the intracellular trafficking of iron and heme intermediates. His research team has been instrumental in identifying Mitoferrin1 (Slc25a37) as the major iron transporter in the erythroid mitochondria. His group has identified a network of solute carriers and chaperon proteins that give a more complete understanding of mitochondrial iron and heme trafficking critical for normal erythropoiesis and their relevance to human anemias.

Bio

Dr Paw received his A.B. (Biochemistry) degree from University of California, Berkeley, and his M.D. and Ph.D. (Biological Chemistry) degrees from University of California, Los Angeles School of Medicine.
He completed his residency in pediatrics at Boston Children's Hospital and a fellowship in pediatric hematology-oncology at Boston Children's Hospital and the Dana-Farber Cancer Institute. He conducted postdoctoral research fellowship at Boston Children’s Hospital. He is currently an Associate Professor of Medicine at Harvard Medical School and an attending physician in Pediatric Oncology at Boston Children’s Hospital and Dana-Farber Cancer Institute.