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Scientists at Monash University, in Melbourne, have solved a mystery in molecular biology that could lead to a new way to treat cancer. A team led by developmental biologist Professor Christophe Marcelle, of the university’s Australian Regenerative Medicine Institute, has discovered a key molecular pathway that determines the fate of embryonic stem cells in chickens. […]
Heal thyself – Monash University stem cell finding points the way to a faster repair of muscle-based injury and disease
Melbourne scientists have found the first direct evidence for a speculated stem-cell based mechanism of muscle repair, in work that could lead to longer, healthier lives for the elderly and muscular dystrophy sufferers. The study, led by Professor Peter Currie, Director of the Australian Regenerative Medicine Institute (ARMI) at Monash University (Melbourne), could also lead […]
First year PhD student, Celia Vandestadt, has had an eventful few months at ARMI. “During that time, I’ve been on radio, shook hands with the Prime Minister and spent time with the most extraordinary group of young leaders.” But that shouldn’t take anything away from the achievement of being awarded an inaugural Westpac Scholarship to […]
Having only recently arrived at ARMI, Hozana Castillo has already mastered the institute’s commercial size coffee machine. “Melbourne and I have two things in common,” she told us. “We both know what real coffee is.” Hozana is an early career postdoc and a Science Without Borders scholar from Brazil. After accepting a position at ARMI, […]
Mikaël Martino’s research paper, “Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration,” discusses how the innate immune system modulates the regeneration process, focusing, in particular, on injury to bone tissue. See the Resources column to the right to view the full paper as a PDF.
Did you know the human body needs to produce one million blood cells every second of every day to live? In patients with leukaemia, rapidly multiplying abnormal white blood cells outcompete healthy cells, leaving the body starved of oxygen and lacking immunity. Treatment for this disease includes chemotherapy that kill the leukaemia cells, but as […]
For bone marrow transplantation, stem cells are routinely harvested from healthy donors and used to treat patients with cancers including leukaemia. Current harvesting methods take a long time and require injections of a growth factor to boost stem cell numbers. This often leads to side effects. The discovery, published today in Nature Communications , reduces […]
(Image from left to right: Jose Polo (Co-corresponding), Helen Abud (Co-corresponding), Christian Nefzger (Co-First), Thierry Jarde (Co-First)) Like most organs, our gut is made out of many different cell types. In a normal state, these cells work together to enable normal gut function. However, the gut can be subjected to a variety of diseases that can […]
First appeared in The Guardian, by James Bourne, 1 March 2016 ‘The care and welfare of animals are of paramount concern to every researcher.’ Photograph: Graeme Robertson for the Guardian “… and what do you do for a living James?” Before answering this question I can predict a range of responses to my answer. Some people lean forward […]
ARMI strives for two key results for our effort: to create new knowledge in stem cell and regenerative research that can improve patients lives, and to share our discoveries with the world. With this in mind, ARMI has teamed up with Nature Publishing Group to publish a new journal: npj Regenerative Medicine, an open access journal, sharing […]